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Initial responses includeinjury and death of ciliated cells in the conducting airwaysand squamous epithelial cells in the parenchyma. And it is not simply gallows humor but,as Warner observes, a way to take the intensity out of our powerful compan-ion so we are not blinded by fear, so that we can make some personal spacefor the forging of some new story or the reinforcing of an old story aboutourselves, forged from the darkest, most difficult, fires so often found at theend of our mysterious lives. to generate the same ejection pressure a dilatedventricle has to develop higher wall tension. Approximately98% of the T cells undergo this apoptosis and are thenphagocytosed by the macrophages. Olfactory defects in PDdo not progress markedly with development of motormanifestations (Doty, 2007b) and do not correlate wellwith most other manifestations of the disease (Verbaanet al., 2008), except with autonomic defects (Goldsteinet al., 2010) and cognitive dysfunction, including mem-ory impairment (Baba et al., 2011).
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